Publication List
(〜2002）

Paper Articles

Wakayama, T., Maruyama, Y., Imamura, K. and Fukuta, K.(1993) Penetration of the Zona Pellucida of Eggs of Different Species by Spermatozoa of the Japanese Field Vole, Microtus montebelli. J. Reprod. Dev. 39:319-323.

Wakayama, T., Maruyama, Y., Imamura, K., Kurohmaru, M., Hayashi, Y. and Fukuta, K. (1994) In Vivo and In Vitro Development of Early Stage Embryos in the Japanese Field Vole, Microtus montebelli. J. Reprod. Fertil. 101:663-666.

Wakayama, T., Tanemura, K., Suto, J., Imamura, K., Fukuta, K., Mori, H., Kuramoto, K., Kurohmaru, M. and Hayashi, Y. (1995) Production of term offspring by in vitro fertilization using old mouse spermatozoa. J. Vet. Med. Sci. 57:545-547.

Suto, J., Wakayama, T., Imamura, K., Goto, S. and Fukuta, K. (1995) Incomplete development of the spleen and the deformity in the chimeras between asplenic mutant (Dominant hemimelia) and normal mice. Teratology. 52: 71-77.

Wakayama, T., Suto, J., Matsubara, Y., Imamura, K., Fukuta, K., Toyoda, Y., Kurohmaru, M. and Hayashi, Y. (1995) In vitro fertilization and embryo development of Japanese Field Vole, Microtus montebelli. J. Reprod. Fertil. 104: 63-68.

Endo, H., Hondo, E., Yamagiwa, D., Wakayama, T., Kurohmaru, M. and Hayashi, Y. (1996) Distribution of cardiac musculature in the pulmonary venous wall of three species of the genus Mustela. Mammal Study 21: 37-42.

Ogura, A., Yamamoto, Y., Matsuda, J., Suzuki, O., Wakayama, T., Kimura, H. and Asano, T. (1996) In vitro fertilization and microinsemination with round spermatids for propagation of nephrotic genes in mice. Theriogenology 45: 1141-1149.
Suto, J., Wakayama, T., Imamura, K., Goto, S. and Fukuta, K. (1996) Observation on the skeletal malformations caused by the Dh (Dominant hemimelia) gene in mice. Exp. Anim. 45:95-98.

Suto, J., Wakayama, T., Imamura, K., Goto, S. and Fukuta, K. (1996) High lethality of F1 male Dh/+ mice from the cross between female DDD and male Dh/+. Exp. Anim. 45:99-101.

Wakayama, T., Suto, J., Imamura, K., Toyoda, Y., Kurohmaru, M. and Hayashi, Y. (1996) Effect of hypotaurine on In vitro fertilization and production of term offspring from in vitro fertilized ova of the Japanese Field Vole, Microtus montebelli. Biol. Reprod. 54: 625-630.

Wakayama, T., Ogura, A., Suto, J., Matsubara, Y., Kurohmaru, M., Hayashi, Y. and Yanagimachi, R. (1996) Penetration by field vole spermatozoa of mouse and hamster zonae pellucidae without acrosome reaction. J. Reprod. Fertil. 107: 97-102.

Tanemura, K., Wakayama, T., Kuramoto, K., Hayashi, Y. and Ogura, A. (1997) Birth of normal young by microinsemination with frozen-thawed round spermatids collected from aged azoospermic mice. Lab. Anim. Sci. 47: 203-204.

Wakayama, T., Hayashi, Y. and Ogura, A. (1997) The female pronucleus derived from the second polar body can participate in full embryonic development. J. Reprod. Fertil. 110: 263-266.

Ogura, A., Wakayama, T., Suzuki, O., Shin, T.Y., Matsuda, J. and Kobayashi, Y. (1997) Chromosomes of mouse primary spermatocytes undergo meiotic divisions after incorporation into homologous immature oocytes. Zygote. 5: 177-182.

Wakayama, T., Uehara, T., Hayashi, Y. and Yanagimachi, R. (1997) The response of mouse oocytes injected with sea urchin spermatozoa. Zygote. 5: 229-234.

Cummins, J.M., Wakayama, T. and Yanagimachi, R. (1997) Fate of microinjected sperm components in the mouse oocyte and embryo. Zygote. 5: 301-308.

Wakayama, T., Whittengham, D.G. and Yanagimachi, R. (1998) Production of normal offspring from mouse oocytes injected with spermatozoa cryopreserved with or without cryoprotection. J. Reprod. Fertil. 112:11-17.

Dozortsev, D., Wakayama, T., Ermilov, A. and Yanagimachi, R. (1998) Intracytoplasmic sperm injection in the rat. Zygote. 6:143-147.

Cummins, J.M., Wakayama, T. and Yanagimachi, R. (1998) Fate of microinjected immature sperm mitochondria in the mouse oocyte and embryo. Zygote. 6:213-222.

Tateno, H., Wakayama, T., Ward, W. S. and Yanagimachi, R. (1998) Can alcohol retain the reproductive and genetic potential of sperm nuclei?: chromosome analysis os mouse spermatozoa stored in alcohol. Zygote. 6:233-238.

Wakayama, T. and Yanagimachi, R. (1998) Fertilizability and developmental ability of mouse oocytes with reduced amount of cytoplasm. Zygote 6:341-346.

Wakayama, T. and Yanagimachi, R. (1998) The first polar body can be used the production of normal offspring. Biol. Reprod. 59:100-104.

Wakayama, T. and Yanagimachi, R. (1998) Development of normal mice from oocytes injected with freeze-dried spermatozoa. Nature biotechnology 16:639-641. (Cover article of issue).

Wakayama, T., Perry, A.C.F., Zuccotti, M. and Yanagimachi, R. (1998) Full term development of mice from enucleated oocytes injected with cumulus cell nuclei. Nature 394:369-374. (Cover article of issue).

Perry A.C.F., Wakayama, T. and Yanagimachi, R. (1999) A novel trans-complementation assay suggests full mammalian oocyte activation is co-ordinately initiated by multiple, sub-membrane sperm components. Bio. Repord. 60:747-755.

Perry A.C.F., Wakayama T., Kishikawa H., Kasai T., Okabe M., Toyoda Y., Yanagimachi R. (1999) Mammalian transgenesis by intracytoplasmic sperm injection. 　 Science 284: 1180-1183.

Wakayama T. and Yanagimachi R. (1999) Cloning of male mice from adult tail-tip cells. Nature Genetics 22:127-128.

Wakayama T. Rodriguez I., Perry ACF. Yanagimachi R. and Mombaerts P. (1999) Mice cloned from embryonic stem cells. Proc. Natl. Acad. Sci. USA 26:14984-14989.

Kishikawa H., Wakayama T. and Yanagimachi R. (1999) Comparison of oocyte-activating agents for mouse cloning. Cloning 1:153-159

Perry ACF. Wakayama T. Cooke IM. and Yanagimachi R. (2000) Mammalian oocyte activation by the synergistic action of discrete sperm head components:Induction of calcium transients and involvement of proteolysis. Dev. Biol. 217: 386-393

Wakayama T., Tateno H., Mombaerts P. and Yanagimachi R. (2000) Nuclear transfer into mouse zygotes. Nature Genetics. 24:108-109

Rideout III W. M., Wakayama T., Wutz A., Eggan K., Jackson-Grusby L., Dausman J., Yanagimachi R. and Jaenisch R. (2000) Generation of mice from wild-type and targeted ES cells by nuclear cloning. Nature Genetics 24:109-110.

Tamashiro KLK, Wakayama T., Blanchard RJ, Blanchard DC, and Yanagimachi R. (2000) Postnatal growth and behavioral development of mice cloned from adult cumulus cells. Biol. Reprod. 63:328-334.

Ogura A., Inoue K., Takano K., Wakayama T. and Yanagimachi R. (2000) Birth of Mice after Nuclear Transfer by Electrofusion using Tail Tip Cells. Mol. Reprod. Dev. 57:55-59.

Wakayama T., Shinkai Y., Tamashiro KLK., Niida H., Blanchard DC., Blanchard RJ., Ogura A., Tanemura K., Tachibana M., Perry ACF., Colgan DF., Mombaerts P. and Yanagimachi R. (2000) Cloning of mice to six generations. Nature 407: 318-319.

Wakayama T. and Yanagimachi R. (2001) Mouse cloning with nucleus donor cells of different age and type. Mol. Reprod. Dev. 58: 376-383

Wakayama T. and Yanagimachi R. (2001) Effect of cytokinesis inhibitor, DMSO and the timing of oocyte activation on mouse cloning using cumulus cell nuclei. Reproduction 122:49-60

Wakayama T., Tabar, V., Rodriguez I., Perry ACF., Studer, L., Mombaerts P. (2001) Differentiation of embryonic stem cell lines generated from adult somatic cells by nuclear transfer. Science. 292:740-743

Ohgane J, Wakayama T, Kogo Y, Senda S, Hattori N, Tanaka S, Yanagimachi R, Shiota K. (2001) DNA methylation variation in cloned mice. Genesis 30:45-50

Kawase Y, Iwata T, Toyoda Y, Wakayama T, Yanagimachi R, Suzuki H (2001) Comparison of intracytoplasmic sperm injection for inbred and hybrid mice Mol. Reprod. Dev. 60:74-78

Perry ACF, Rothman A, de Las Heras JI, Feinstein P, Mombaerts P, Cooke HJ, Wakayama T. (2001) Efficient metaphase II transgenesis with different transgene archetypes. Nat Biotechnol. 19:1071-1073

Tanaka S, Oda M, Toyoshima Y, Wakayama T, Tanaka M, Yoshida N, Hattori N, Ohgane J, Yanagimachi R, Shiota K (2001) Placentomegaly in cloned mouse concepti caused by expansion of the spongiotrophoblast layer. Biol Reprod. 65:1813-1821.

Yamazaki Y, Wakayama T, Yanagimachi R. (2001) Contribution of cumulus cells and serum to the maturation of oocyte cytoplasm as revealed by intracytoplasmic sperm injection (ICSI). Zygote 2001 9:277-282.

Tamashiro KL, Wakayama T, Akutsu H, Yamazaki Y, Lachey JL, Wortman MD, Seeley RJ, D'Alessio DA, Woods SC, Yanagimachi R, Sakai RR. (2002) Cloned mice have an obese phenotype not transmitted to their offspring. Nat Med 8:262-267 (Cover article of issue).





Reviews

Perry AC, Wakayama T. (2002) Untimely ends and new beginnings in mouse cloning. Nat Genet 30:243-244.



Books

Wakayama T. and Yanagimachi R. (2000) Use of freeze-thaw and freeze-dry spermatozoa for intra-cytoplasmic sperm injection. Genetic Diversity and conservation of animal genetic resources. (Oono K. eds.) pp. 185-193. Research council secretariat of MAFF, Japan.

Wakayama T. and Yanagimachi R. (2001) Mouse cloning using different types of somatic cells. Cloning animal and placentation. (R. M Roberts, R. Yanagimachi, T. Kariya and K. Hashizume eds) pp.27-29. Yokendo Ltd. Japan.

Wakayama T. and Perry ACF. (2002) Cloning mice: perspective and prospective. ( J.Cibelli, RP Lanza, KHS Campbell, MD West, ed) Principles of Cloning. Academic Press. pp.301-341. 2002

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