Publication List

→Before 2002

Paper Articles

Wakayama S, Cibelli JB, Wakayama T (2003) Effect of timing of the removal of oocyte chromosomes before or after injection of somatic nucleus on development of NT embryos. Cloning and stem cells 5: 181-189.

Singh U, Fohn LE, Wakayama T, Ohgane J, Steinhoff C, Lipkowitz B, Schulz R, Orth A, Ropers HH, Behringer RR, Tanaka S, Shiota K, Yanagimachi R, Nuber UA, Fundele R. (2004) Different molecular mechanisms underlie placental overgrowth phenotypes caused by interspecies hybridization, cloning, and Esx1 mutation. Developmental Dynamics. 230, 149-164.

Yanagimachi R., Wakayama T., Kishikawa H., Fimia GM., Monaco L. and Sassone-Corsi P. (2004) Production of fertile offspring from genetically infertile male mice. Proc. Natl. Acad. Sci. USA 101, 1691-1695.

Ohgane J, Wakayama T, Senda S, Yamazaki Y, Inoue K, Ogura A, Marh J, Tanaka S, Yanagimachi R, Shiota K. (2004) The Sall3 locus is an epigenetic hotspot of aberrant DNA methylation associated with placentomegaly of cloned mice. Genes Cells.;9:253-260

Lanza R, Moore MA, Wakayama T, Perry AC, Shieh JH, Hendrikx J, Leri A, Chimenti S, Monsen A, Nurzynska D, West MD, Kajstura J, Anversa P. (2004) Regeneration of the Infarcted Heart With Stem Cells Derived by Nuclear Transplantation. Circulation Research. 94:820-827

Satoshi Kishigami, Sayaka Wakayama, Nguyen Van Thuan and Teruhiko Wakayama. (2004) Similar time restriction for ICSI and ROSI into activated oocytes for efficient offspring production Biol Reprod. 70:1863-1869

Ohta H, Wakayama T, Nishimune Y. (2004) Commitment of Fetal Male Germ Cells to Spermatogonial Stem Cells During Mouse Embryonic Development. Biol Reprod. 70: 1286-1291

Ohta H., and Wakayama T. (2004) Full-term development of offspring using ectopically produced haploid germ cells from fetal male germ cells. J. Reprod. Dev. 50:429-437.

Senda S, Wakayama T, Yamazaki Y, Ohgane J, Hattori N, Tanaka S, Yanagimachi R, Shiota K. (2004) Skewed X-inactivation in cloned mice. Biochem Biophys Res Commun. 321:38-44.

Wakayama S, Thuan NV, Kishigami S, Ohta H, Mizutani E, Hikichi T, Miyake M, Wakayama T. (2004) Production of offspring from one-day-old oocytes stored at room temperature. J. Reprod. Dev. 50:627-637.

Kishigami S, Thuan NV, Wakayama S, Hikichi T, Wakayama T. (2004) A new separation method of the round-spermatid cytoplasm before ROSI in mouse. Zygote 12: 321-327

Mochida K, Wakayama T, Takano K, Noguchi Y, Yamamoto Y, Suzuki O, Matsuda J, and Ogura A (2005) Birth of Offspring after Transfer of Mongolian Gerbil (Meriones unguiculatus) Embryos Cryopreserved by Vitrification. Mol. Reprod. Dev. 70: 464-470.

Van Thuan N, Wakayama S, Kishigami S, and Wakayama T (2005) New Preservation Method for Mouse Spermatozoa Without Freezing. Biol. Reprod. 72, 444?450.

Hikichi T, Kishigami S, Thuan NV, Ohta H, Mizutani E, Wakayama S, Wakayama T. (2005) Round spermatids stained with mitotracker can be used to produce offspring more simply. Zygote. 2005 13:55-61.

Wakayama S, Ohta H, Kishigami S, Van Thuan N, Hikichi T, Mizutani E, Miyake M, Wakayama T. (2005) Establishment of Male and Female Nuclear Transfer Embryonic Stem Cell Lines from Different Mouse Strains and Tissues. Biol. Reprod. 72, 932-936.

Wakayama S, Kishigami S, Van Thuan N, Ohta H, Hikichi T, Mizutani E, Yanagimachi R, Wakayama T. (2005) Propagation of an Infertile Hermaphrodite Mouse Lacking Germ Cells, Using Nuclear Transfer and Embryonic Stem Cell Technology. Proc. Natl. Acad. Sci. USA 102:29-33. (Cover article of issue)

Ohta H, Wakayama T. Generation of Normal Progeny by Intracytoplasmic Sperm Injection Following Grafting of Testicular Tissue from Cloned Mice that Died Postnatally. Biol Reprod. 2005 73:390-395

Fujita, K. Ohta, H. Tsujimura, A. Takao, T. Miyagawa, Y. Takada, S. Matsumiya, K. Wakayama, T. Okuyama, A. (2005) Transplantation of spermatogonial stem cells isolated from leukemic mice restores fertility without inducing leukemia. J Clin Invest. 115:1855-1861

Mizutani E, Ohta H, Kishigami S, Van Thuan N, Hikichi T, Wakayama S, Sato E, Wakayama T Generation of progeny from embryonic stem cells by microinsemination of male germ cells from chimeric mice. Genesis. 2005 43:34-42.

Singh U, Sun T, Shi W, Schulz R, Nuber UA, Varanou A, Hemberger MC, Elliott RW, Ohta H, Wakayama T, Fundele R. (2005) Expression and Functional Analysis of Genes Deregulated in Mouse Placental Over Growth Models: Car2 and Ncam1. Dev. Dynamics 234:1034-1045

Wakayama, S., E. Mizutani, S. Kishigami, N. V. Thuan, H. Ohta, T. Hikichi, H. T. Bui, M. Miyake and T. Wakayama (2005) Mice Cloned by Nuclear Transfer from Somatic and ntES Cells Derived from the Same Individuals, J Reprod Dev, 51: 765-772.

Kishigami S, Thuan NV, Hikichi T, Ohta H, Wakayama S, Mizutani E, Wakayama T. Epigenetic abnormalities of the mouse paternal zygotic genome associated with microinsemination of round spermatids Dev Biol 2006 289: 195-205.

Tamada, H., N. V. Thuan, P. Reed, D. Nelson, N. Katoku-Kikyo, J. Wudel, T. Wakayama and N. Kikyo (2006) Chromatin decondensation and nuclear reprogramming by nucleoplasmin, Mol Cell Biol, 26: 1259-1271.

Kishigami S, Mizutani E, Ohta H, Hikichi T, Thuan NV, Wakayama S, Bui HT, Wakayama T, Significant improvement of mouse cloning technique by treatment with trichostatin A after somatic nuclear transfer. Biochem Biophys Res Commun 2006 340: 183-189.

Van Thuan, N., Wakayama, S., Kishigami, S. and Wakayama, T. (2006) Donor Centrosome Regulation of Initial Spindle Formation in Mouse Somatic Cell Nuclear Transfer: Roles of Gamma-Tubulin and Nuclear Mitotic Apparatus Protein 1, Biol Reprod in press,

Van Thuan, N., S. Wakayama, S. Kishigami, H. Ohta, T. Hikichi, E. Mizutani, H. T. Bui and T. Wakayama (2006) Injection of Somatic Cell Cytoplasm into Oocytes Before ICSI Impairs Full-Term Development and Increases Placental Weight in Mice, Biol Reprod, in press.



Reviews

Wakayama T. (2003) Cloned mice and embryonic stem cell lines generated from adult somatic cells by nuclear transfer. Oncology Research. 13:309-314.

Tamashiro KL, Wakayama T, Yamazaki Y, Akutsu H, Woods SC, Kondo S, Yanagimachi R, Sakai RR.　 (2003) Phenotype of Cloned Mice: Development, Behavior, and Physiology.　Exp Biol Med. 228:1193-1200

Wakayama T. (2004) On the road to therapeutic cloning. Nature Biotechnology. 22: 399-400

Wakayama S. Wakayama T. (2005) Embryonic stem cell lines from somatic cell nuclei via nuclear transfer. J. Mamm. Ova. Res. 22: 152-158.

Kishigami S. Wakayama S. Thuan NV, Wakayama T. Cloned mice and ES cell establishment from adult somatic cell Human Cell 2006 In press


Books

Wakayama T (2004) Establishment of ES cell lines from adult somatic cells by nuclear transfer (Celis JE, ed) Cell Biology: A laboratory handbook, Third edition. Academic press